Myrcene is our terpene for today’s discussion. It is the most common terpene found in most cannabis.
Myrcene – Myrcene’s major effect is sedative in nature, resulting in relaxed muscles and a reduction of pain. This is of obvious value in a number of conditions involving spasticity, seizure activity, or hyperactivity (including Attention-Deficit/Hyperactivity Disorder [ADHD]), and encompasses common and often debilitating diseases like fibromyalgia and Post Traumatic Stress Disorder (PTSD). Cannabis strains with high myrcene levels are often described as tasting spicy, earthy, and musky. Myrcene also carries sweet undertones, which have been compared to ripe mango and other fruity flavors.
Many doctors and researchers recommend myrcene for patients who suffer insomnia, restlessness, and a multitude of forms of anxiety. According to Leafly, “Pair this famously anti-inflammatory terpene with herbal concoctions containing lemongrass or hops for a powerful calm that may put those numbered sheep to rest.”
Myrcene is also a proven anti-depressant and anti-inflammatory. Like another terpene, limonene, myrcene has an effect on the permeability of cell membranes, meaning it acts as a regulator of other terpenes and cannabinoids, enhancing or buffering their effects and potency (similar to how CBD modulates THC).
This unique capability of myrcene allows it to increase the volume of THC molecules that reaches CB1 receptors in the brain and central nervous system, effectively magnifying the potency of this cannabis molecule’s psychoactive effect—while simultaneously amplifying its medicinal efficacy. In this respect, myrcene is an excellent demonstration of the entourage effect.
Multiple beneficial interactions between myrcene and several major cannabinoids, including THC and CBD can be found below.
- CBD + myrcene: Decreases inflammation, fights cancer, reduces pain.
- CBG + myrcene: Anti-cancer.
- THC + myrcene: Analgesic (reduces pain) and muscle relaxant; enhanced sedative and tranquilization benefits.